Beta-RAM 部分应用文献列表
Molecular imaging of glycan chains couples cell-wall polysaccharide architecture to bacterial cell morphology
Nature Communications volume 9, Article number: 1263 (2018)
2′-O-methylation in mRNA disrupts tRNA decoding during translation elongation
Nature Structural & Molecular Biology volume 25, pages208–216 (2018)
Loss of an Androgen-Inactivating and Isoform-Specific HSD17B4 Splice Form Enables Emergence of Castration-Resistant Prostate Cancer
Cell Reports,Volume 22, Issue 3, p809–819, 16 January 2018
Functional silencing of HSD17B2 in prostate cancer promotes disease progression
CLINICAL CANCER RESEARCH September 18, 2018
Direct metabolic interrogation of dihydrotestosterone biosynthesis from adrenal precursors in primary prostatectomy tissues
CLINICAL CANCER RESEARCH July 21, 2017
Redirecting abiraterone metabolism to fine-tune prostate cancer anti-androgen therapy
Nature volume533, pages547–551 (26 May 2016)
N6-methyladenosine in mRNA disrupts tRNA selection and translation-elongation dynamics
Nature Structural & Molecular Biology 23, 110–115,2016
Accuracy of genetic code translation and its orthogonal corruption by aminoglycosides and Mg2+ions
Nucleic Acids Research, Volume 46, Issue 3, 16 February 2018, Pages 1362–1374
Molecular mechanism of viomycin inhibition of peptide elongation in bacteria
PNAS January 26, 2016 113 (4) 978-983
Stabilin-1 and Stabilin-2 are specific receptors for the cellular internalization of phosphorothioate-modified antisense oligonucleotides (ASOs) in the liver
Nucleic Acids Research, Volume 44, Issue 6, 7 April 2016, Pages 2782–2794
Spatially Organized Enzymes DriveCofactor-Coupled Cascade Reactions
J. Am. Chem. Soc., 2016, 138 (9), pp 3012–3021
Ribosomal Peptide Syntheses from Activated Substrates Reveal Rate Limitation by an Unexpected Step at the Peptidyl Site
J Am Chem Soc. 2016 Dec 7;138(48):15587-15595
Conversion of abiraterone to D4A drives anti-tumour activity in prostate cancer
Nature volume523, pages347–351 (16 July 2015)
Making water-soluble integral membrane proteins in vivo using an amphipathic protein fusion strategy
Nature Communications volume6, Article number: 6826 (2015)
Structural Insights into Assembly and Regulation of the Plasma Membrane Phosphatidylinositol 4-Kinase Complex
Developmental cell,Volume 28, Issue 1, 13 January 2014
Targeted delivery of antisense oligonucleotides to hepatocytes using triantennary N-acetyl galactosamine improves potency 10-fold in mice
Nucleic Acids Research, Volume 42, Issue 13, 29 July 2014, Pages 8796–8807
A Gain-of-Function Mutation in DHT Synthesis in Castration-Resistant Prostate Cancer
Cell ,Volume 154, Issue 5, 29 August 2013, Pages 1074-1084
Measurement of phosphoinositides in the zebrafish Danio rerio
Nature Protocols volume8, pages1058–1072 (2013)
Development of orally active inhibitors of protein and cellular fucosylation
PNAS April 2, 2013. 110 (14) 5404-5409
Mycobacterium tuberculosis is extraordinarily sensitive to killing by a vitamin C-induced Fenton reactio
Nature Communications volume4, Article number: 1881 (2013)
Proc Natl Acad SciUSA January 3, 2012 109 (1) 131-136
Structural insights into the stereochemistry of the cyclooxygenase reaction
Nature 405, 97–101,2000
Nature Medicine 6, 1043–1047,2000